CD Genomics is highlighting its RNA sequencing service for researchers studying gene expression, transcriptome organization and RNA biology. The service supports projects requiring quantitative and sequence-based analysis of RNA molecules across biomedical, pharmaceutical, agricultural and molecular biology research.
RNA sequencing uses next-generation sequencing to examine the sequences and relative abundance of RNA molecules in a biological sample. Unlike DNA-focused methods such as amplicon sequencing or whole exome sequencing, RNA-seq provides information about transcriptional activity under specific biological conditions, treatments or developmental stages.
CD Genomics provides transcriptome profiling and gene expression analysis through a range of library and sequencing strategies. These include total RNA sequencing, mRNA sequencing, Poly(A) RNA-Seq, whole transcriptome sequencing, targeted RNA-Seq, small RNA-related workflows and long-read transcript sequencing.
The appropriate approach depends on the study objective and RNA composition of the sample. mRNA-focused methods can support gene expression quantification, while total RNA workflows can include broader RNA populations such as long noncoding RNAs and other noncoding transcripts. Specialized protocols may be selected for low-input samples, degraded material, transcript-end analysis or specific RNA classes.
Short-read sequencing can support transcript abundance measurement, differential expression analysis and the detection of transcript-level features. Depending on the library design and analytical workflow, projects may also examine novel transcripts, alternative splicing, transcript isoforms and selected gene-fusion events. These results are influenced by RNA integrity, library preparation, sequencing depth, reference annotation and the bioinformatics pipeline.
For studies requiring full-length transcript information, PacBio Iso-Seq and other long-read approaches can reduce reliance on reconstructing transcript structures from short fragments. Long-read data may assist with isoform characterization and the analysis of complex transcript architectures when read length, sample quality and coverage are suitable.
RNA sequencing can be applied to cells, fresh or frozen tissue, FFPE material, blood, serum, plasma, urine, cell media, exosomes, saliva, cerebrospinal fluid and stool. Sample preservation and RNA quality remain important considerations because degradation, genomic DNA contamination and variable RNA composition can affect library preparation and downstream interpretation.
CD Genomics describes a workflow that may include RNA isolation, library construction, sequencing, quality control, alignment or transcript assembly, expression analysis and report generation. Typical deliverables include original sequencing data, experimental results and a data analysis report. Optional downstream analysis may include pathway interpretation, transcript annotation and comparative expression analysis.
CD Genomics offers specialized RNA omics and sequencing solutions covering transcriptomics, noncoding RNA research, long-read sequencing, epitranscriptomics and related bioinformatics services.
About CD Genomics:
CD Genomics provides genomics sequencing, transcriptomics, genotyping and bioinformatics services for pharmaceutical, biotechnology, academic and research customers. Its capabilities cover targeted sequencing, exome and genome studies, RNA analysis, microbiome research, single-cell sequencing and related genomic data analysis.
Media Contact:
Contact Person: Dianna Gellar
Email: contact@cd-genomics.com
Phone: +1 631 259 7705
Website: rna.cd-genomics.com
Address: Shirley, NY, USA
For Research Use Only. Not for use in clinical diagnosis, treatment or individual health assessment.